Dual Lead-lined Synthesis Hot Cell

The hot cell employs a fully isolated protective design with a clean, arc-shaped stainless steel interior, which is fully compliant with the requirements for the synthesis of positron-emitting radioactive drugs. It features high-standard lead shielding and biological cleanliness safety requirements, meeting both radiation safety environmental standards and ensuring a cGMP clean pharmaceutical environment during the synthesis of positron-emitting radioactive drugs.

The hot cell is composed of three structural parts:

★The control area, located at the top of the hot cell, is equipped with an independent ventilation system, hot cell control unit, gas valves, and an internal radiation dose monitoring and interlock unit.

★The working area, situated in the middle of the hot cell, allows operators to enter through the front shielded door. The spacious internal dimensions are designed to accommodate the installation of all synthesizers available on the market.

★The auxiliary area, located at the bottom of the hot cell, provides the auxiliary functional requirements for the hot cell.

Main Technical Specifications:

The working area complies with cGMP biological cleanliness standards.

The double-chamber synthesis lead cell is constructed from seamless welded stainless steel.
Cleanliness level: Class C
Negative pressure: -50 Pa to -200 Pa
Airflow: 300 m³/h
Sealing: Secondary sealing
Supply air: High-efficiency filter
Exhaust air: Activated carbon filter

Lead shielding complies with ICRP radiation environmental safety standards (lead equivalence customizable)

Front shielding: 75 mm Pb
Side shielding: 60 mm Pb
Target Line Shielding: 50 mm Pb equivalent shielding
Radiation dose at the surface of the hot cell: <5 μSv/h @ 3 Ci-F18
Radiation dose at 30 cm from the hot cell: <1 μSv/h @ 3 Ci-F18

Ergonomically designed operational control panel

Hot cell control: Centralized integrated control with a full-touch human-machine interface
Visual observation: Independent high-definition display for real-time monitoring
Negative pressure indicator: Analogue negative pressure gauge

Dimensions:

Internal dimensions: W850 * D619 * H700 mm
External dimensions: W1185 * D1117 * H2400 mm
Additional accessories: Lighting, UV light, ozone sterilization unit, target line sealing flange, airtight power outlets, etc.